Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | PPARD | Q03181 | 4/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844628 | 0.82 | TSHR (0.50) | TSHRALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL9333344 | 0.81 | KDM4E (0.35) | TSHRALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL21197441 | 0.78 | TSHR (0.53) | TSHRALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL9459955 | 0.77 | TSHR (0.45) | TSHRALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL9459286 | 0.77 | ALDH1A1 (0.45) | TSHRALDH1A1KDM4EPOLBMAPT | |
| Hydrochloric Acid SCHEMBL9460000 | 0.75 | MAPT (0.43) | TSHRALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL7824143 | 0.73 | PRKCA (0.51) | TSHRALDH1A1LMNAPRKCACES2 | |
| SCHEMBL10424178 | 0.73 | PRKCA (0.49) | TSHRALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL10596465 | 0.71 | KDM4E (0.42) | TSHRALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL10550196 | 0.71 | NLRP3 (0.44) | TSHRALDH1A1KDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422537-B1 | Cyclohexenone compounds, process for their preparation and their use as herbicides or plant growth regulators | BASF AG (DE) | 1994-05-11 | — | — | EP | disclosed |
| EP-0422493-B1 | Process for the preparation of cyclohexane trione carboxylic acid thiol esters and intermediate products | BASF AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| US-5194650-A | Chemical intermediates which can be hydrolyzed to form arylcyclohexadionethiocarboxylic S-ester as bioregulators | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| US-5130453-A | Multistage reaction of acylcyclohexadione, reaction with hydroxylamine derivative and mercaptan | BASF AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |
| US-5085689-A | Preemergence and postemergence treatment | BASF AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | disclosed |
| EP-0422537-A1 | Cyclohexenone compounds, process for their preparation and their use as herbicides or plant growth regulators | BASF Aktiengesellschaft (DE) | 1991-04-17 | — | — | EP | disclosed |
| EP-0422493-A1 | Process for the preparation of cyclohexane trione carboxylic acid thiol esters and intermediate products | BASF Aktiengesellschaft (DE) | 1991-04-17 | — | — | EP | disclosed |