Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 19/20 | 0.62 |
| ▸ | GGPS1 | O95749 | 8/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16091938 | 1.00 | FDPS (0.62) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL9333595 | 0.98 | FDPS (0.61) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL3976360 | 0.92 | FDPS (0.57) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL18330273 | 0.86 | FDPS (0.47) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| Olpadronic Acid SCHEMBL138988 | 0.83 | FDPS (0.58) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL9313278 | 0.82 | FDPS (0.77) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL11952578 | 0.82 | FDPS (0.47) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL16091907 | 0.82 | FDPS (0.42) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL14029188 | 0.82 | FDPS (0.55) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| Olpadronic Acid SCHEMBL232124 | 0.81 | FDPS (0.56) | FDPSGGPS1PDE3AAGTR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592488-A1 | DIMETHYLAMINO-HYDROXY-ALKAN DIPHOSPHONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | INSTITUTO GENTILI S.P.A. (IT) | 1994-04-20 | — | — | EP | claimed |
| WO-1993000348-A1 | DIMETHYLAMINO-HYDROXY-ALKAN DIPHOSPHONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ISTITUTO GENTILI S.P.A. (IT) | 1993-01-07 | — | — | WO | claimed |
| EP-0592488-A1 | DIMETHYLAMINO-HYDROXY-ALKAN DIPHOSPHONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | INSTITUTO GENTILI S.P.A. (IT) | 1994-04-20 | — | — | EP | disclosed |
| WO-1993000348-A1 | DIMETHYLAMINO-HYDROXY-ALKAN DIPHOSPHONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ISTITUTO GENTILI S.P.A. (IT) | 1993-01-07 | — | — | WO | disclosed |