Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.43 |
| ▸ | HK1 | P19367 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29361524 | 0.94 | MAPT (0.39) | HKDC1HK1RAD52MAPTRAB9A | |
| SCHEMBL29176 | 0.94 | MAPT (0.39) | HKDC1HK1RAD52MAPTRAB9A | |
| Fluoride Ion SCHEMBL7937209 | 0.90 | RAB9A (0.40) | HKDC1HK1RAD52MAPTRAB9A | |
| Iodide SCHEMBL7946268 | 0.90 | MAPT (0.37) | HKDC1HK1RAD52MAPTRAB9A | |
| Iodide SCHEMBL7946269 | 0.90 | MAPT (0.37) | HKDC1HK1RAD52MAPTRAB9A | |
| Bromide SCHEMBL7948386 | 0.90 | MAPT (0.37) | HKDC1HK1RAD52MAPTRAB9A | |
| SCHEMBL9116348 | 0.90 | MAPT (0.37) | HKDC1HK1RAD52MAPTRAB9A | |
| Bromide SCHEMBL7948384 | 0.90 | MAPT (0.37) | HKDC1HK1RAD52MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL7937215 | 0.90 | RAB9A (0.40) | HKDC1HK1RAD52MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL1185945 | 0.90 | MAPT (0.37) | HKDC1HK1RAD52MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322236-B1 | Catalytic process for preparing optically active threonine | TAKASAGO PERFUMERY CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0297752-B1 | PROCESS OF PREPARING OPTICALLY ACTIVE ALCOHOL | Takasago International Corporation (JP) | 1992-09-16 | — | — | EP | disclosed |
| EP-0295890-B1 | PROCESS OF PREPARING OPTICALLY ACTIVE ALCOHOL | Takasago International Corporation (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-4933482-A | HYDROGENATION OF BETA-KETO ACID IN PRESENCE OF RUTHENIUM PHOSPHINE COMPLEX | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1990-06-12 | — | — | US | disclosed |
| US-4916252-A | OPTICALLY ACTIVE PHOSPHINE-RUTHENIUM HYDROGENATION CATALYST | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1990-04-10 | — | — | US | disclosed |