Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10599951 | 0.83 | KDM4E (0.45) | BRD4KDM4EBLMLMNACYP1A2 | |
| SCHEMBL12853990 | 0.80 | PTPRC (0.44) | BRD4KDM4EBLMLMNACYP1A2 | |
| SCHEMBL17124510 | 0.75 | KDM4E (0.59) | KDM4EBLMLMNACYP1A2POLB | |
| SCHEMBL26259977 | 0.72 | BRD4 (0.50) | BRD4KDM4EBLMLMNACYP1A2 | |
| SCHEMBL26259990 | 0.72 | BRD4 (0.45) | BRD4KDM4EBLMLMNACYP1A2 | |
| SCHEMBL679952 | 0.72 | CYP19A1 (0.55) | KDM4EBLMLMNAPOLBHIF1A | |
| SCHEMBL1232419 | 0.72 | ALDH1A1 (0.57) | KDM4ETDP1KMT2AMEN1GAA | |
| SCHEMBL10720213 | 0.72 | PSMD14 (0.41) | BRD4KDM4EBLMLMNACYP1A2 | |
| SCHEMBL1177593 | 0.72 | BRD4 (0.37) | BRD4KDM4EBLMLMNACYP1A2 | |
| SCHEMBL9556910 | 0.72 | PTPRC (0.40) | BRD4KDM4EBLMLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348684-A | Organosilylalkyl or organosilylalkenyl compounds, process for preparing them and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-20 | — | — | US | disclosed |
| EP-0355008-B1 | Organosilylalkyl or -alkenyl compounds, process for their preparation and their use in liquid-crystal mixtures | HOECHST AG (DE) | 1994-04-13 | — | — | EP | disclosed |
| EP-0355008-A2 | Organosilylalkyl or -alkenyl compounds, process for their preparation and their use in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-21 | — | — | EP | disclosed |