Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331754 | 0.88 | NR4A1 (0.44) | CYP3A4CYP1A2CYP2C19TLR7L3MBTL1 | |
| SCHEMBL9582221 | 0.82 | MAOB (0.41) | CYP3A4TLR7L3MBTL1RAB9ANPBWR1 | |
| SCHEMBL4493478 | 0.82 | NPBWR1 (0.46) | TLR7NPBWR1MCHR1MAPTLMNA | |
| SCHEMBL9847110 | 0.81 | AR (0.43) | PLA2G7AR | |
| SCHEMBL9332364 | 0.81 | HTR2A (0.36) | CYP3A4CYP1A2CYP2C19TLR7L3MBTL1 | |
| SCHEMBL9332068 | 0.80 | TLR8 (0.44) | CYP3A4CYP1A2CYP2C19TLR7ATM | |
| SCHEMBL9331767 | 0.79 | TDP1 (0.47) | CYP3A4CYP1A2CYP2C19TLR7MAPT | |
| SCHEMBL8693586 | 0.79 | MEN1 (0.47) | CYP3A4CYP1A2CYP2C19RAB9AMAPT | |
| SCHEMBL10518064 | 0.79 | THRB (0.40) | CYP3A4CYP1A2CYP2C19L3MBTL1RAB9A | |
| SCHEMBL4496108 | 0.78 | AR (0.42) | TLR7L3MBTL1RAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448206-B1 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LTD (GB) | 1994-12-28 | — | — | EP | disclosed |
| US-5306692-A | Herbicidal indazole and benzimidazole compounds | ZENECA LIMITED (GB) | 1994-04-26 | — | — | US | disclosed |
| EP-0448206-A2 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |