Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10443317 | 0.92 | AR (0.47) | ARTRPV4PGRPLA2G7 | |
| SCHEMBL10443289 | 0.91 | AR (0.45) | AR | |
| SCHEMBL9331754 | 0.84 | NR4A1 (0.44) | — | |
| SCHEMBL8323124 | 0.83 | AR (0.39) | ARTRPV4PGRSLC22A12 | |
| SCHEMBL9847119 | 0.81 | TRPV4 (0.43) | ARTRPV4PGRPLA2G7SLC22A12 | |
| SCHEMBL9334657 | 0.81 | CYP3A4 (0.37) | ARPLA2G7 | |
| SCHEMBL11041547 | 0.81 | KIF11 (0.41) | AR | |
| SCHEMBL8320983 | 0.81 | AR (0.40) | ARTRPV4PGRPLA2G7SLC22A12 | |
| SCHEMBL10442993 | 0.79 | AR (0.50) | ARPLA2G7 | |
| SCHEMBL9582221 | 0.79 | MAOB (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457140-A2 | Phenoxyphenyl sulfonyl compounds | BAYER AG (DE) | 1991-11-21 | — | — | EP | disclosed |
| EP-0379915-A1 | Substituted phenoxybenzonitrile derivatives, processes for their preparation and their use as herbicides and plant growth regulators | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |