Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335164 | 0.84 | LMNA (0.50) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL28085233 | 0.81 | POLB (0.41) | CNR2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL5000624 | 0.81 | LMNA (0.44) | CNR2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL27941958 | 0.79 | AR (0.43) | CNR2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL28452847 | 0.79 | MAPT (0.47) | CNR2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL27874980 | 0.79 | POLB (0.40) | CNR2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL11111178 | 0.79 | AHR (0.46) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL16113228 | 0.77 | RAB9A (0.41) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL1310734 | 0.77 | ALDH1A1 (0.61) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL29498757 | 0.77 | ALDH1A1 (0.61) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427404-B1 | Anthanthrone derivatives | ZENECA LTD (GB) | 1994-05-25 | — | — | EP | disclosed |
| EP-0427404-A2 | Anthanthrone derivatives | ZENECA LIMITED (GB) | 1991-05-15 | — | — | EP | disclosed |
| US-4128586-A | Catalytic reduction of aromatic sulfonyl halides with hydrogen sulfide to yield aromatic thiols | ALLIED CHEMICAL CORPORATION (US) | 1978-12-05 | — | — | US | disclosed |
| US-4072584-A | PIGMENTS, RUBBER | ALLIED CHEMICAL CORPORATION (US) | 1978-02-07 | — | — | US | disclosed |