Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 9/20 | 0.53 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.41 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11363113 | 1.00 | RNPEP (0.61) | RNPEPFOLH1CPB2GSTK1GPR84 | |
| SCHEMBL5669221 | 1.00 | RNPEP (0.61) | RNPEPFOLH1CPB2GSTK1GPR84 | |
| SCHEMBL27622250 | 0.98 | RNPEP (0.59) | RNPEPFOLH1CPB2GSTK1GPR84 | |
| SCHEMBL13057108 | 0.98 | RNPEP (0.64) | RNPEPFOLH1CPB2GSTK1MAPT | |
| SCHEMBL28722923 | 0.95 | RNPEP (0.61) | RNPEPFOLH1CPB2GSTK1 | |
| SCHEMBL11366455 | 0.90 | — | — | |
| SCHEMBL11161171 | 0.90 | RNPEP (0.73) | RNPEPFOLH1CPB2GSTK1GPR84 | |
| SCHEMBL11163066 | 0.90 | RNPEP (0.73) | RNPEPFOLH1CPB2GSTK1GPR84 | |
| SCHEMBL11159608 | 0.87 | RNPEP (0.76) | RNPEPFOLH1CPB2GPR84FFAR1 | |
| SCHEMBL5476409 | 0.82 | RNPEP (0.68) | RNPEPFOLH1CPB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128117-A | Compositions comprising O-acetylsalicyl derivatives of aminosugars and amino acids | YU RUEY J (US) | 2008-02-20 | — | — | CN | claimed |
| CN-100367949-C | Melanin extinguisher | OGA RES INC (JP) | 2008-02-13 | — | — | CN | claimed |
| CN-1896072-A | Preparation of R-sulcaprylic acid and its salt | LAIER BIOLOG CHEMICAL CO LTD N (CN) | 2007-01-17 | — | — | CN | claimed |
| CN-1681490-A | Melanin extinguisher | OGA RES INC (JP) | 2005-10-12 | — | — | CN | claimed |
| CN-107427433-B | Tyrosinase activity inhibitor and skin external preparation | 捷鸥化妆品株式会社 | 2020-10-20 | — | — | CN | disclosed |
| US-10632089-B2 | Tyrosinase activity inhibitor and external preparation for skin | JO COSMETICS CO., LTD. (JP) | 2020-04-28 | — | — | US | disclosed |
| US-20180071239-A1 | TYROSINASE ACTIVITY INHIBITOR AND EXTERNAL PREPARATION FOR SKIN | JO COSMETICS CO., LTD. (JP) | 2018-03-15 | — | — | US | disclosed |
| CN-104877127-B | A kind of eight arms polyethyleneglycol derivative, preparation method and its bio-related substance of modification | 厦门赛诺邦格生物科技股份有限公司 | 2017-11-10 | — | — | CN | disclosed |
| CN-103565801-B | For treating compositions and the said composition application in treatment ocular disease of eyeground macular edema | 陈井然 | 2016-08-31 | — | — | CN | disclosed |
| CN-101765370-B | Lipoic acid derivatives | CORNERSTONE PHARMACEUTICALS IN | 2014-06-25 | — | — | CN | disclosed |
| CN-103415286-A | Compounds and methods for treating pain | AKRON MOLECULES GMBH | 2013-11-27 | — | — | CN | disclosed |
| CN-102089276-A | Modulation of enzyme structure, activity and/or expression level | ROBERT SHORR | 2011-06-08 | — | — | CN | disclosed |
| CN-1681490-A | Melanin extinguisher | OGA RES INC (JP) | 2005-10-12 | — | — | CN | disclosed |
| CN-1537109-A | Novel modifications of the trometamol salt of R-lipoic acid and process for preparing them | 维亚特里斯两合公司 | 2004-10-13 | — | — | CN | disclosed |
| US-20040092586-A1 | Novel a-lipoic acid derivative and use thereof | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1371640-A1 | NOVEL A-LIPOIC ACID DERIVATIVE AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 2003-12-17 | — | — | EP | disclosed |
| CN-1377267-A | Retard form containing 2-lipoic acid (derivatives) | SUEDDEUTSCHE KALKSTICKSTOFF (DE) | 2002-10-30 | — | — | CN | disclosed |
| EP-1124820-A1 | LIPOIC ACID DERIVATIVES AND THEIR USE IN TREATMENT OF DISEASE | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000024734-A1 | LIPOIC ACID DERIVATIVES AND THEIR USE IN TREATMENT OF DISEASE | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2000-05-04 | — | — | WO | disclosed |
| US-5705192-A | FLUIDIZED BEDS AND SPRAYING THEN REMOVAL OF SOLVENT AND FORMING TABLETS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1998-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10632089-B2 | Tyrosinase activity inhibitor and external preparation for skin | TYR, SOD1, CAT | RNPEP 181/4885FOLH1 2094/4885CPB2 1249/4885 |
| US-20180071239-A1 | TYROSINASE ACTIVITY INHIBITOR AND EXTERNAL PREPARATION FOR SKIN | TYR, SOD1, CAT | RNPEP 181/4885FOLH1 2094/4885CPB2 1249/4885 |
| US-20040092586-A1 | Novel a-lipoic acid derivative and use thereof | TYR, SERPINB1, LPO | RNPEP 44/4885FOLH1 2480/4885CPB2 833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.