Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.67 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | CPA1 | P15085 | 1/20 | 0.51 |
| ▸ | CPA2 | P48052 | 1/20 | 0.51 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27953598 | 0.93 | CPB2 (0.58) | CPB2GRIK1MAOACPA1CPA2 | |
| SCHEMBL19438906 | 0.87 | GRIK1 (0.67) | CPB2GRIK1MAOAFOLH1CYP1A2 | |
| SCHEMBL1862995 | 0.86 | GRIK1 (0.61) | CPB2GRIK1FOLH1CYP1A2 | |
| SCHEMBL4023050 | 0.85 | FOLH1 (0.66) | CPB2CPA1FOLH1CYP1A2ERAP2 | |
| SCHEMBL4016996 | 0.85 | FOLH1 (0.66) | CPB2CPA1FOLH1CYP1A2ERAP2 | |
| SCHEMBL4017000 | 0.85 | FOLH1 (0.66) | CPB2CPA1FOLH1CYP1A2ERAP2 | |
| SCHEMBL1860416 | 0.84 | GRIK1 (0.68) | CPB2GRIK1FOLH1CYP1A2LAP3 | |
| SCHEMBL1857365 | 0.84 | CYP1A2 (0.61) | CPB2GRIK1CPA1FOLH1CYP1A2 | |
| SCHEMBL8868645 | 0.84 | GRIK1 (0.51) | CPB2GRIK1CPA1FOLH1CYP1A2 | |
| SCHEMBL7077500 | 0.84 | MMP2 (0.55) | CPB2GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594692-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL IN THE TREATMENT OF PANIC ATTACKS | WARNER-LAMBERT COMPANY (US) | 1994-05-04 | — | — | EP | disclosed |