SCHEMBL9336752

SCHEMBL9336752

O=S(=O)(O)c1ccc(-c2coc(S)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.39
TP53 P04637 5/20 0.39
POLB P06746 3/20 0.39
LMNA P02545 3/20 0.38
ENPP2 Q13822 1/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
PKM P14618 1/20 0.38
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.37
NT5E P21589 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
THRB P10828 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10341439 0.76 ENPP3 (0.55) HSD11B1TP53TSHRALDH1A1SMN1; SMN2
SCHEMBL3171676 0.69 LMNA (0.65) POLBLMNAENPP2TSHRALDH1A1
SCHEMBL447639 0.69 LMNA (0.65) POLBLMNAENPP2TSHRALDH1A1
SCHEMBL525918 0.69 LMNA (0.65) POLBLMNAENPP2TSHRALDH1A1
SCHEMBL29990536 0.69 LMNA (0.65) POLBLMNAENPP2TSHRALDH1A1
SCHEMBL28310262 0.68 LMNA (0.72) POLBLMNAENPP2KMT2AMEN1
SCHEMBL14366888 0.68 LMNA (0.52) POLBLMNAENPP2TSHRALDH1A1
SCHEMBL824421 0.67 KDM4E (0.47) POLBLMNAENPP2TSHRALDH1A1
SCHEMBL9333789 0.67 CA12 (0.46) LMNAKMT2ATSHRALDH1A1NT5E
SCHEMBL9302694 0.66 LMNA (0.62) POLBLMNAENPP2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0377889-B1 Silver halide recording material AGFA GEVAERT AG (DE) 1994-05-18 EP disclosed
US-5089381-A SILVER HALIDE RECORDING MATERIAL AGFA-GEVAERT AG (DE) 1992-02-18 US disclosed
EP-0377889-A1 Silver halide recording material Agfa-Gevaert AG (DE) 1990-07-18 EP disclosed
EP-0373339-A1 Silver halide recording material Agfa-Gevaert AG (DE) 1990-06-20 EP disclosed