Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523919 | 0.91 | PARP1 (0.49) | DRD1 | |
| SCHEMBL9335569 | 0.90 | KMT2A (0.44) | — | |
| SCHEMBL9386887 | 0.85 | SGMS2 (0.58) | SGMS2 | |
| SCHEMBL7770156 | 0.79 | DRD1 (0.45) | DRD1 | |
| Fumaric Acid SCHEMBL9868255 | 0.78 | MEN1 (0.44) | DRD1 | |
| Fumaric Acid SCHEMBL9868247 | 0.78 | MEN1 (0.44) | DRD1 | |
| SCHEMBL4446308 | 0.77 | MRGPRX4 (0.58) | HSD17B10 | |
| SCHEMBL9868989 | 0.77 | MEN1 (0.42) | HSD17B10 | |
| SCHEMBL9332773 | 0.76 | MYC (0.50) | HSD17B10 | |
| SCHEMBL7505146 | 0.75 | HSD17B10 (0.59) | HSD17B10DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533695-B1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER (US) | 1994-10-05 | — | — | EP | disclosed |
| US-5322847-A | Inhibit platelet activating factor, block leukotriene D4 receptors | PFIZER INC. (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0533695-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY. | PFIZER (US) | 1993-03-31 | — | — | EP | disclosed |
| EP-0530207-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | Pfizer Limited (GB) | 1993-03-10 | — | — | EP | disclosed |
| WO-1991017162-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | PFIZER LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |
| WO-1991017163-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER INC. (US) | 1991-11-14 | — | — | WO | disclosed |