Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337098 | 0.91 | SGMS2 (0.43) | DRD1 | |
| SCHEMBL9335569 | 0.89 | KMT2A (0.44) | — | |
| SCHEMBL9386887 | 0.85 | SGMS2 (0.58) | SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL7770156 | 0.80 | DRD1 (0.45) | DRD1 | |
| SCHEMBL9523968 | 0.76 | HSD17B10 (0.48) | SMN1; SMN2DRD1 | |
| Fumaric Acid SCHEMBL9868255 | 0.76 | MEN1 (0.44) | DRD1RAB9A | |
| Fumaric Acid SCHEMBL9868247 | 0.76 | MEN1 (0.44) | DRD1RAB9A | |
| SCHEMBL7774816 | 0.74 | DRD1 (0.49) | DRD1 | |
| SCHEMBL9332789 | 0.74 | KLKB1 (0.51) | LMNADRD1 | |
| SCHEMBL9525557 | 0.74 | MAPK1 (0.51) | HTTDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530207-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | Pfizer Limited (GB) | 1993-03-10 | — | — | EP | disclosed |
| WO-1991017162-A1 | IMIDAZOPYRIDINE PAF ANTAGONISTS | PFIZER LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |