Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.56 |
| ▸ | MMP2 | P08253 | 4/20 | 0.56 |
| ▸ | MMP9 | P14780 | 4/20 | 0.56 |
| ▸ | LCK | P06239 | 2/20 | 0.47 |
| ▸ | P4HB | P07237 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9342457 | 0.87 | MAOA (0.54) | MMP1MMP2MMP9CYP1B1MAOA | |
| SCHEMBL9337686 | 0.84 | HSD17B3 (0.54) | CYP1B1MAOAMAOBPOLBMAPT | |
| SCHEMBL9339814 | 0.84 | MAOB (0.58) | CYP1B1MAOAMAOB | |
| SCHEMBL9778685 | 0.83 | APP (0.45) | MMP1MMP2MMP9CYP1B1MAOA | |
| SCHEMBL9339436 | 0.83 | NFE2L2 (0.61) | CYP1B1MAOAMAOBMAPTRAB9A | |
| SCHEMBL9341559 | 0.83 | CYP1A2 (0.53) | CYP1B1MAOAMAOBMAPTRAB9A | |
| SCHEMBL9338542 | 0.82 | CYP1B1 (0.64) | MMP1MMP2MMP9CYP1B1MAOA | |
| SCHEMBL25199667 | 0.81 | CYP1B1 (0.69) | MMP1MMP2MMP9P4HBCYP1B1 | |
| SCHEMBL8829843 | 0.81 | CYP1B1 (0.69) | MMP1MMP2MMP9P4HBCYP1B1 | |
| SCHEMBL31233274 | 0.81 | CYP1B1 (0.69) | MMP1MMP2MMP9P4HBCYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |