Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340999 | 0.86 | MAPT (0.44) | MAPTCYP1B1GPR183AKR1C3MAOA | |
| SCHEMBL9337744 | 0.82 | MAPT (0.42) | MAPTCA1CA2CYP1B1MAOA | |
| SCHEMBL10337730 | 0.81 | MAPT (0.60) | MAPTCA1CYP1B1MAOAMAOB | |
| SCHEMBL9338517 | 0.80 | GPR183 (0.52) | MAPTCYP1B1GPR183MAOAMAOB | |
| SCHEMBL9337686 | 0.79 | HSD17B3 (0.54) | MAPTCYP1B1MAOAMAOBPOLB | |
| SCHEMBL9339700 | 0.79 | PTGS1 (0.43) | MAPTCA1CA2CYP1B1MAOA | |
| SCHEMBL9338080 | 0.79 | PTGS2 (0.43) | MAPTCA1CA2CYP1B1MAOA | |
| Hydrochloric Acid SCHEMBL11815678 | 0.79 | GPR183 (0.51) | MAPTCYP1B1GPR183MAOAMAOB | |
| SCHEMBL9339914 | 0.77 | MAPT (0.41) | MAPTCA1CA2CYP1B1MAOA | |
| SCHEMBL9338084 | 0.77 | MAOA (0.43) | MAPTCA1CA2CYP1B1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |