Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339436 | 0.86 | NFE2L2 (0.61) | PTGS2PTGS1MAPTNFE2L2EGFR | |
| SCHEMBL9341825 | 0.85 | NFE2L2 (0.42) | PTGS2PTGS1MAPTNFE2L2EGFR | |
| SCHEMBL9341603 | 0.85 | NFE2L2 (0.60) | PTGS2MAPTNFE2L2CYP1B1MAOA | |
| SCHEMBL10337730 | 0.82 | MAPT (0.60) | MAPTNFE2L2EGFRCA1CYP1B1 | |
| SCHEMBL9338525 | 0.82 | NFE2L2 (0.38) | PTGS2MAPTNFE2L2CYP1B1MAOA | |
| SCHEMBL9338041 | 0.81 | NFE2L2 (0.62) | PTGS2MAPTNFE2L2CYP1B1MAOA | |
| SCHEMBL9339700 | 0.80 | PTGS1 (0.43) | PTGS2PTGS1MAPTCA1CA2 | |
| SCHEMBL9337744 | 0.80 | MAPT (0.42) | PTGS2PTGS1MAPTEGFRCA1 | |
| SCHEMBL9339914 | 0.79 | MAPT (0.41) | PTGS2PTGS1MAPTEGFRCA1 | |
| SCHEMBL9338084 | 0.79 | MAOA (0.43) | PTGS2PTGS1MAPTEGFRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |