Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341825 | 0.86 | NFE2L2 (0.42) | NFE2L2PTGS2MAPTMAOAMAOB | |
| SCHEMBL10337730 | 0.83 | MAPT (0.60) | NFE2L2MAPTMAOAMAOBCYP1B1 | |
| SCHEMBL9341603 | 0.82 | NFE2L2 (0.60) | NFE2L2PTGS2MAPTMAOAMAOB | |
| SCHEMBL13869121 | 0.81 | PTGS2 (0.72) | NFE2L2PTGS2MAPTMAOAMAOB | |
| SCHEMBL9338080 | 0.81 | PTGS2 (0.43) | NFE2L2PTGS2MAPTMAOAMAOB | |
| SCHEMBL9339436 | 0.80 | NFE2L2 (0.61) | NFE2L2PTGS2MAPTMAOAMAOB | |
| SCHEMBL9341895 | 0.79 | MMP1 (0.55) | MAPTPOLBCXCL12ALDH1A1CYP3A4 | |
| SCHEMBL9338058 | 0.79 | MAOB (0.66) | MAPTMAOAMAOBCYP1B1CYP1A2 | |
| SCHEMBL11823920 | 0.79 | MAOB (0.66) | MAPTMAOAMAOBCYP1B1CYP1A2 | |
| SCHEMBL10498942 | 0.78 | KCNK2 (0.43) | PTGS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |