Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.47 |
| ▸ | LPL | P06858 | 2/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339736 | 0.96 | HDAC4 (0.44) | HDAC4MEF2DLPLLIPGTHRA | |
| SCHEMBL9342510 | 0.95 | HDAC4 (0.43) | HDAC4MEF2DLPLLIPGTHRA | |
| SCHEMBL9338680 | 0.92 | HDAC4 (0.39) | HDAC4MEF2DTHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL10498322 | 0.91 | HDAC4 (0.47) | HDAC4MEF2DLPLLIPGTHRA | |
| SCHEMBL10498154 | 0.90 | THRA (0.44) | THRATHRB | |
| SCHEMBL10497777 | 0.90 | THRA (0.46) | HDAC4MEF2DLPLLIPGTHRA | |
| SCHEMBL9337818 | 0.89 | HDAC4 (0.45) | HDAC4MEF2DSMN1; SMN2ALDH1A1PTGS2 | |
| SCHEMBL9342772 | 0.85 | THRA (0.44) | THRATHRBSMN1; SMN2 | |
| SCHEMBL9342497 | 0.85 | HDAC4 (0.43) | HDAC4MEF2DLPLLIPGTHRA | |
| SCHEMBL10498348 | 0.84 | CYP1A2 (0.44) | HDAC4MEF2DTHRATHRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |