Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.43 |
| ▸ | LPL | P06858 | 2/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 7/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339736 | 0.99 | HDAC4 (0.44) | HDAC4MEF2DLPLLIPGTHRA | |
| SCHEMBL10498154 | 0.95 | THRA (0.44) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497777 | 0.95 | THRA (0.46) | HDAC4MEF2DLPLLIPGTHRA | |
| SCHEMBL9338139 | 0.95 | HDAC4 (0.47) | HDAC4MEF2DLPLLIPGTHRA | |
| SCHEMBL10498322 | 0.94 | HDAC4 (0.47) | HDAC4MEF2DLPLLIPGTHRA | |
| SCHEMBL9342497 | 0.90 | HDAC4 (0.43) | HDAC4MEF2DLPLLIPGTHRA | |
| SCHEMBL9338680 | 0.90 | HDAC4 (0.39) | HDAC4MEF2DTHRB | |
| SCHEMBL9337818 | 0.87 | HDAC4 (0.45) | HDAC4MEF2DTDP1 | |
| SCHEMBL10498768 | 0.86 | THRA (0.47) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL9338240 | 0.86 | THRA (0.49) | THRATHRBATG4BPLA2G1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |