Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9338139 | 0.92 | HDAC4 (0.47) | HDAC4MEF2DSMN1; SMN2PTGS2ALDH1A1 | |
| SCHEMBL9337818 | 0.92 | HDAC4 (0.45) | HDAC4MEF2DSMN1; SMN2SLC6A19PTGS2 | |
| SCHEMBL9339736 | 0.91 | HDAC4 (0.44) | HDAC4MEF2DTHRB | |
| SCHEMBL9342510 | 0.90 | HDAC4 (0.43) | HDAC4MEF2DTHRB | |
| SCHEMBL9342184 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2PTGS2MAOBMAOAALDH1A1 | |
| SCHEMBL10498154 | 0.85 | THRA (0.44) | THRBKMT2A | |
| SCHEMBL9341575 | 0.84 | MAOB (0.46) | SMN1; SMN2PTGS2MAOBMAOAALDH1A1 | |
| SCHEMBL10497777 | 0.84 | THRA (0.46) | HDAC4MEF2DTHRB | |
| SCHEMBL9779017 | 0.83 | MAOB (0.48) | SMN1; SMN2PTGS2MAOBMAOAALDH1A1 | |
| SCHEMBL9338665 | 0.83 | SLC6A19 (0.51) | SMN1; SMN2SLC6A19MAOBMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |