Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31725232 | 0.83 | CA1 (0.43) | ALDH1A1 | |
| SCHEMBL31073290 | 0.83 | CA1 (0.43) | ALDH1A1 | |
| SCHEMBL31073356 | 0.83 | CA1 (0.43) | ALDH1A1 | |
| SCHEMBL8686880 | 0.80 | NPC1 (0.42) | — | |
| SCHEMBL10514359 | 0.79 | — | — | |
| SCHEMBL18056394 | 0.76 | CA2 (0.37) | — | |
| SCHEMBL21556841 | 0.75 | APLNR (0.31) | APLNR | |
| SCHEMBL31073192 | 0.75 | APLNR (0.42) | ALDH1A1APLNR | |
| SCHEMBL31042359 | 0.75 | APLNR (0.42) | ALDH1A1APLNR | |
| SCHEMBL26125642 | 0.75 | NPC1 (0.33) | ALDH1A1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598750-A1 | INDOLES | Pfizer Limited (GB) | 1994-06-01 | — | — | EP | disclosed |
| WO-1993002050-A1 | INDOLES | PFIZER LIMITED (GB) | 1993-02-04 | — | — | WO | disclosed |