Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339925 | 0.88 | HDAC4 (0.41) | LMNASMN1; SMN2MAOBMAOAHDAC4 | |
| SCHEMBL9342270 | 0.83 | SMN1; SMN2 (0.46) | LMNASMN1; SMN2PTGS2PTGS1ALOX5 | |
| SCHEMBL9342014 | 0.81 | MAOB (0.51) | LMNASMN1; SMN2PTGS2PTGS1ALOX5 | |
| SCHEMBL9342426 | 0.81 | PTGS2 (0.44) | LMNASMN1; SMN2PTGS2PTGS1ALOX5 | |
| SCHEMBL9341440 | 0.79 | SMN1; SMN2 (0.46) | LMNASMN1; SMN2PTGS2PTGS1ALOX5 | |
| SCHEMBL9342184 | 0.78 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2PTGS2PTGS1ALOX5 | |
| SCHEMBL9338074 | 0.78 | MAOA (0.43) | LMNASMN1; SMN2PTGS2PTGS1ALOX5 | |
| SCHEMBL9338546 | 0.77 | PTGS2 (0.44) | LMNASMN1; SMN2PTGS2PTGS1ALOX5 | |
| SCHEMBL9337782 | 0.77 | CYP1A1 (0.45) | PTGS2PTGS1ALOX5MAOBHDAC6 | |
| SCHEMBL9337818 | 0.77 | HDAC4 (0.45) | LMNASMN1; SMN2PTGS2PTGS1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |