Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9338368 | 0.88 | LMNA (0.43) | HDAC4MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9342218 | 0.85 | MAPT (0.41) | HDAC4MEF2DNR1H4MAPTNPC1 | |
| SCHEMBL9337818 | 0.85 | HDAC4 (0.45) | HDAC4MEF2DMAPTNPC1RAB9A | |
| SCHEMBL9779017 | 0.82 | MAOB (0.48) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9338665 | 0.82 | SLC6A19 (0.51) | MAPTSMN1; SMN2KMT2ACYP1B1ALDH1A1 | |
| SCHEMBL9338586 | 0.81 | NPSR1 (0.48) | HDAC4MEF2DMAPTNPC1RAB9A | |
| SCHEMBL9338406 | 0.80 | BCL2 (0.43) | MAPTNPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL9338680 | 0.80 | HDAC4 (0.39) | HDAC4MEF2DMAPTNPC1RAB9A | |
| SCHEMBL9339939 | 0.79 | MAOB (0.54) | KMT2ACYP1B1ALDH1A1LMNAMEN1 | |
| SCHEMBL9338013 | 0.79 | PTGS2 (0.44) | HDAC4MEF2DMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |