Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DUSP1 | P28562 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337966 | 0.89 | ALOX5 (0.41) | CYP1A1CYP1B1SMN1; SMN2LMNAMAPT | |
| SCHEMBL9341978 | 0.85 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL9342783 | 0.84 | SMN1; SMN2 (0.39) | CYP1A1CYP1B1SMN1; SMN2LMNAMAPT | |
| SCHEMBL9342710 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAMAPTHTTNPC1 | |
| SCHEMBL9339663 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL9337681 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMAPTHTTRAB9A | |
| SCHEMBL9338556 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL9342426 | 0.78 | PTGS2 (0.44) | SMN1; SMN2LMNAMAPTHTTALOX5 | |
| SCHEMBL9779017 | 0.77 | MAOB (0.48) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL9342565 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAMAPTHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |