Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337818 | 0.88 | HDAC4 (0.45) | MAOBMAOAALOX5PTGS1PTGS2 | |
| SCHEMBL9342426 | 0.87 | PTGS2 (0.44) | MAOBMAOAALOX5PTGS1PTGS2 | |
| SCHEMBL9342457 | 0.86 | MAOA (0.54) | MAOBMAOAALOX5PTGS1PTGS2 | |
| SCHEMBL9338665 | 0.86 | SLC6A19 (0.51) | MAOBMAOAATMMAPTSMN1; SMN2 | |
| SCHEMBL9338586 | 0.84 | NPSR1 (0.48) | MAOBMAOAALOX5PTGS1PTGS2 | |
| SCHEMBL9338680 | 0.83 | HDAC4 (0.39) | MAOBMAOAPTGS1PTGS2NPC1 | |
| SCHEMBL9338406 | 0.83 | BCL2 (0.43) | PTGS1PTGS2NPC1RAB9AMAPT | |
| SCHEMBL9339939 | 0.82 | MAOB (0.54) | MAOBMAOALMNAHTTKDM4E | |
| SCHEMBL9338013 | 0.82 | PTGS2 (0.44) | MAOBMAOAPTGS1PTGS2NPC1 | |
| SCHEMBL9339925 | 0.82 | HDAC4 (0.41) | MAOBMAOANPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |