Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152442 | 0.74 | POLB (0.47) | CASP3KDM4EALDH1A1HPGDGAA | |
| SCHEMBL1727593 | 0.74 | UGCG (0.47) | CASP3KDM4EALDH1A1GAAGSK3B | |
| SCHEMBL12394337 | 0.72 | POLB (0.45) | CASP3KDM4EALDH1A1HPGDGAA | |
| SCHEMBL5070001 | 0.71 | NR1H2 (0.52) | CASP3GAATTRCES1SIRT2 | |
| SCHEMBL6152233 | 0.70 | HPRT1 (0.45) | CASP3KDM4EALDH1A1HPGDGAA | |
| SCHEMBL12725181 | 0.69 | NR1H2 (0.50) | CASP3ALDH1A1GSK3B | |
| SCHEMBL7068310 | 0.69 | PTGS2 (0.51) | KDM4EALDH1A1HPGDGAAGSK3B | |
| SCHEMBL14620065 | 0.68 | POLB (0.41) | CASP3KDM4EALDH1A1HPGDGAA | |
| SCHEMBL9338640 | 0.68 | STK10 (0.45) | KDM4EALDH1A1GAAGSK3BPTPRC | |
| SCHEMBL6152286 | 0.68 | COMT (0.42) | CASP3KDM4EALDH1A1HPGDTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354869-A | Fluorescent dyes | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1994-10-11 | — | — | US | disclosed |