SCHEMBL1727593

SCHEMBL1727593

COc1ccccc1C1=C2C(=O)N(C)C(c3ccccc3OC)=C2C(=O)N1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UGCG Q16739 3/20 0.47
PTPRC P08575 1/20 0.46
PTPN1 P18031 1/20 0.46
PRMT1 Q99873 1/20 0.45
ALDH1A1 P00352 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MAPT P10636 2/20 0.43
APP P05067 1/20 0.43
KDM4E B2RXH2 1/20 0.43
USP2 O75604 1/20 0.43
DUSP3 P51452 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NR1H3 Q13133 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9338640 0.92 STK10 (0.45) UGCGPTPRCPTPN1PRMT1ALDH1A1
SCHEMBL12845107 0.91 TP53 (0.44) UGCGPTPRCPTPN1PRMT1ALDH1A1
SCHEMBL12914362 0.76 PRMT1 (0.47) PTPRCPTPN1PRMT1ALDH1A1MEN1
SCHEMBL9338684 0.74 HSD11B1 (0.44) PTPRCALDH1A1KDM4ECA2CA9
SCHEMBL25028103 0.73 HSP90AA1 (0.47) UGCGALDH1A1MEN1KMT2AMAPT
SCHEMBL6152442 0.71 POLB (0.47) PTPN1PRMT1ALDH1A1MEN1KMT2A
SCHEMBL29788337 0.71 CA1 (0.71) ALDH1A1MEN1KMT2AMAPTAPP
SCHEMBL29429633 0.71 CA1 (0.71) ALDH1A1MEN1KMT2AMAPTAPP
SCHEMBL301996 0.71 CA1 (0.71) ALDH1A1MEN1KMT2AMAPTAPP
SCHEMBL12394337 0.69 POLB (0.45) PTPN1PRMT1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5354869-A Fluorescent dyes RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1994-10-11 US claimed
EP-1611207-B1 FLUORESCENT DIKETOPYRROLOPYRROLES BASF SE (DE) 2016-02-03 EP disclosed
WO-2012027650-A3 PALLET DESIGN WITH BUOYANT CHARACTERISTICS ORIA COLLAPSIBLES, LLC (US) 2012-05-10 WO disclosed
EP-1399514-B1 FLUORESCENT DIKETOPYRROLOPYRROLES BASF SE (DE) 2012-01-11 EP disclosed
EP-2212386-B1 DIKETOPYRROLOPYRROLE COCRYSTALS CLARIANT FINANCE BVI LTD (VG) 2011-11-30 EP disclosed
US-8008507-B2 Fluorescent diketopyrrolopyrroles BASF SE Ludwigshafen (DE) 2011-08-30 US disclosed
US-8008507-B2 Fluorescent diketopyrrolopyrroles BASF SE Ludwigshafen (DE) 2011-08-30 US disclosed
US-7906039-B2 Fluorescent diketopyrrolopyrroles BASF SE (DE) 2011-03-15 US disclosed
US-7749404-B2 Fluorescent diketopyrrolopyrroles CIBA SPECIALTY CHEMICALS CORP. (US) 2010-07-06 US disclosed
US-7749404-B2 Fluorescent diketopyrrolopyrroles CIBA SPECIALTY CHEMICALS CORP. (US) 2010-07-06 US disclosed
US-20070010672-A1 Fluorescent diketopyrrolopyrroles CLAP CO., LTD. (KR) 2007-01-11 US disclosed
US-20040171847-A1 From a pyrrolidinone compound; coloring high molecular weight material CIBA SPECIALTY CHEMICALS CORP. 2004-09-02 US disclosed
EP-1425282-A2 PROCESS FOR THE PREPARATION OF DIKETOPYRROLOPYRROLES Ciba SC Holding AG (CH) 2004-06-09 EP disclosed
WO-2003022848-A2 PROCESS FOR THE PREPARATION OF DIKETOPYRROLOPYRROLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-03-20 WO disclosed
EP-0426717-B1 OPTICAL MEMORY RIEDEL DE HAEN AG (DE) 1996-04-24 EP disclosed
US-5354869-A Fluorescent dyes RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1994-10-11 US disclosed
US-5354869-A Fluorescent dyes RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1994-10-11 US disclosed
US-5354869-A Fluorescent dyes RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1994-10-11 US disclosed
EP-0426717-A1 OPTICAL MEMORY. RIEDEL DE HAEN AG (DE) 1991-05-15 EP disclosed
WO-1990001480-A1 OPTICAL MEMORY RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1990-02-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070010672-A1 Fluorescent diketopyrrolopyrroles TYR, QDPR, MC1R UGCG 4298/4885PTPRC 816/4885PTPN1 98/4885
US-20040171847-A1 From a pyrrolidinone compound; coloring high molecular weight material MKI67, PAH, PKLR UGCG 4433/4885PTPRC 1413/4885PTPN1 89/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.