Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12394336 | 0.81 | PPARG (0.44) | CYP1A2CYP2C19POLBBRD4 | |
| SCHEMBL6153208 | 0.79 | RGS4 (0.47) | SIRT2ALDH1A1MEN1POLBKMT2A | |
| SCHEMBL9836026 | 0.78 | PTGS2 (0.50) | PTGS2ALDH1A1KDM4ECYP2C19HSD17B10 | |
| SCHEMBL26332330 | 0.78 | COMT (0.53) | COMTALDH1A1KDM4ETSHRMEN1 | |
| SCHEMBL12394337 | 0.77 | POLB (0.45) | SIRT2SIRT1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL12725183 | 0.76 | PTGS2 (0.49) | PTGS2CYP2C19HSD17B10MEN1POLB | |
| SCHEMBL6152442 | 0.76 | POLB (0.47) | SIRT2SIRT1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL12394320 | 0.75 | KDM4E (0.42) | SIRT2SIRT1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL12394328 | 0.75 | PPARG (0.41) | CYP2C19HSD17B10POLBBRD4 | |
| SCHEMBL6152713 | 0.74 | MCL1 (0.40) | SIRT2SIRT1KDM4ECYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1253151-B1 | Pyrromethene metal complex and light emitting device composition and light emitting devices using the same | TORAY INDUSTRIES (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-6805978-B2 | COMPLEX CONTAINING DIKETOPYRROLO(3,4-C)PYRROLE COMPOUND | TORAY INDUSTRIES, INC. (JP) | 2004-10-19 | — | — | US | disclosed |
| US-20030082406-A1 | Complex containing diketopyrrolo(3,4-c)pyrrole compound | TORAY INDUSTRIES, INC. (JP) | 2003-05-01 | — | — | US | disclosed |
| EP-1253151-A1 | Pyrromethene metal complex and light emitting device composition and light emitting devices using the same | TORAY INDUSTRIES, INC. (JP) | 2002-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030082406-A1 | Complex containing diketopyrrolo(3,4-c)pyrrole compound | PPOX, CPNE4, TP53RK | COMT 1296/4885SIRT2 3722/4885SIRT1 3580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.