Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 7/20 | 0.40 |
| ▸ | CA9 | Q16790 | 7/20 | 0.40 |
| ▸ | CA12 | O43570 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9338989 | 0.85 | CTSD (0.40) | LMNAKMT2AMMP12MMP9POLB | |
| SCHEMBL14342135 | 0.84 | LMNA (0.43) | LMNAKMT2AMMP12MMP9POLB | |
| SCHEMBL26394603 | 0.84 | LMNA (0.44) | LMNAKMT2AMMP12MMP9POLB | |
| SCHEMBL17287141 | 0.84 | LMNA (0.51) | LMNAKMT2AMMP12MMP9POLB | |
| SCHEMBL17287140 | 0.84 | LMNA (0.51) | LMNAKMT2AMMP12MMP9POLB | |
| SCHEMBL23077722 | 0.84 | LMNA (0.51) | LMNAKMT2AMMP12MMP9POLB | |
| SCHEMBL23627066 | 0.84 | LMNA (0.41) | LMNAKMT2AMMP12MMP9POLB | |
| SCHEMBL7302828 | 0.84 | CA2 (0.44) | LMNAKMT2AMMP12MMP9POLB | |
| SCHEMBL9335075 | 0.81 | CA1 (0.42) | LMNAKMT2AMMP12MMP9POLB | |
| SCHEMBL30608555 | 0.81 | LMNA (0.45) | LMNAKMT2AMMP12MMP9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295540-B1 | Solid-phase system containing allylic chains, process for its preparation and its use in solid-phase reactions | ORPEGEN MED MOLEKULARBIOFORSCH (DE) | 1994-05-11 | — | — | EP | disclosed |