Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341135 | 0.93 | ALDH1A1 (0.58) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9343650 | 0.88 | RAB9A (0.50) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9339094 | 0.87 | ALDH1A1 (0.52) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9343005 | 0.85 | MEN1 (0.54) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9339717 | 0.85 | ALDH1A1 (0.53) | SMN1; SMN2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL9339795 | 0.84 | KMT2A (0.58) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9339777 | 0.84 | KMT2A (0.53) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9339184 | 0.81 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL9339746 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL27405958 | 0.81 | KMT2A (0.55) | SMN1; SMN2RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360808-A | Cardiovascular disorders, antispasmodic agents, hypotensive disorders, brains, anticonvulsants and antiepileptics | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-01 | — | — | US | disclosed |
| EP-0556738-A1 | Pyridinylcarbonylaminoalkyl-dihydro-oxo-pyridines, their production and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-25 | — | — | EP | disclosed |
| CN-1075480-A | New aryl carbonylamino alkyl-dihydro-oxo pyridine compounds and production thereof and application | HOECHST AG (US) | 1993-08-25 | — | — | CN | disclosed |