Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339746 | 0.94 | SMN1; SMN2 (0.53) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL9339717 | 0.90 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL9339777 | 0.89 | KMT2A (0.53) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL9343650 | 0.88 | RAB9A (0.50) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL9339116 | 0.87 | SMN1; SMN2 (0.53) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL9343014 | 0.86 | KMT2A (0.51) | KMT2AMEN1LMNAPOLBUSP2 | |
| SCHEMBL9339739 | 0.86 | EPHX2 (0.54) | ALDH1A1KMT2AMEN1LMNAPOLB | |
| SCHEMBL9339795 | 0.86 | KMT2A (0.58) | ALDH1A1KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL9339077 | 0.85 | KDM4E (0.52) | ALDH1A1KMT2ALMNAPOLBTDP1 | |
| SCHEMBL9341043 | 0.84 | KMT2A (0.54) | KMT2AMEN1LMNAPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360808-A | Cardiovascular disorders, antispasmodic agents, hypotensive disorders, brains, anticonvulsants and antiepileptics | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-01 | — | — | US | disclosed |
| EP-0556738-A1 | Pyridinylcarbonylaminoalkyl-dihydro-oxo-pyridines, their production and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-25 | — | — | EP | disclosed |
| CN-1075480-A | New aryl carbonylamino alkyl-dihydro-oxo pyridine compounds and production thereof and application | HOECHST AG (US) | 1993-08-25 | — | — | CN | disclosed |