Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339195 | 0.90 | RAB9A (0.50) | MAPTMEN1KMT2ATSHR | |
| SCHEMBL9335724 | 0.85 | NR4A2 (0.51) | NR4A2MAPTMEN1KMT2AADRB2 | |
| SCHEMBL11546865 | 0.84 | MAPT (0.61) | NR4A2MAPTMEN1KMT2APLA2G4B | |
| SCHEMBL11548347 | 0.84 | MAPT (0.61) | NR4A2MAPTMEN1KMT2APLA2G4B | |
| SCHEMBL11446135 | 0.77 | KMT2A (0.54) | NR4A2MAPTMEN1KMT2AADRB2 | |
| SCHEMBL9335986 | 0.75 | RAB9A (0.52) | MAPTMEN1KMT2ATSHR | |
| SCHEMBL10950578 | 0.75 | MAPT (0.61) | MAPTMEN1KMT2ATSHRMAPK1 | |
| SCHEMBL9337320 | 0.75 | NR4A2 (0.51) | NR4A2MEN1KMT2APLA2G4BTSHR | |
| SCHEMBL14724729 | 0.74 | PLA2G4B (0.56) | PLA2G4BTSHRMAPK1TP53 | |
| SCHEMBL11546333 | 0.74 | CYP1A2 (0.65) | NR4A2MAPTMEN1KMT2APLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394440-B1 | PHENYLCARBOXYLIC ACID DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-4999378-A | Antilipemic, anticholesterol, antidiabetic, treatment of atherosclerosis and obesity | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1991-03-12 | — | — | US | disclosed |
| EP-0394440-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |