Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 3/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 2/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10548663 | 0.86 | LTA4H (0.48) | SOS1FFAR4GAALTA4HMEN1 | |
| SCHEMBL10545474 | 0.82 | FFAR4 (0.43) | SCN9AFFAR4GAASLC6A2SLC6A4 | |
| SCHEMBL9340581 | 0.80 | SOS1 (0.39) | SOS1HSPB1PDE4APDE4BPDE4C | |
| SCHEMBL10545489 | 0.79 | PARP10 (0.47) | HSPB1FDFT1GAASLC6A2SLC6A4 | |
| SCHEMBL351854 | 0.76 | SOS1 (0.58) | SOS1HSPB1PDE4APDE4BPDE4C | |
| SCHEMBL6290683 | 0.76 | SOS1 (0.58) | SOS1HSPB1PDE4APDE4BPDE4C | |
| SCHEMBL6289867 | 0.76 | SOS1 (0.58) | SOS1HSPB1PDE4APDE4BPDE4C | |
| SCHEMBL9340611 | 0.76 | HSPB1 (0.42) | SOS1HSPB1SCN9ASLC6A2SLC6A4 | |
| SCHEMBL5540625 | 0.75 | HSPB1 (0.48) | SOS1HSPB1PDE4APDE4BPDE4C | |
| SCHEMBL755034 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317265-B1 | Novel imidate insecticides | ZENECA INC (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5089623-A | Certain imidate insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-18 | — | — | US | disclosed |
| US-5070210-A | Novel ketenimines as intermediates for insecticides | ICI AMERICAS INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-5045566-A | Phenyl or naphthyl substituted | ICI AMERICAS INC. (US) | 1991-09-03 | — | — | US | disclosed |
| EP-0317265-A2 | Novel imidate insecticides | ZENECA INC. (US) | 1989-05-24 | — | — | EP | disclosed |
| US-4814340-A | 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4661501-A | Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1987-04-28 | — | — | US | disclosed |
| US-4599362-A | 2-aryl-ethyl ether derivatives and insecticidal and acaricidal agents containing said derivatives | MITSUITOATSU CHEMICALS, INC. (JP) | 1986-07-08 | — | — | US | disclosed |