Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27808679 | 0.93 | DNM1 (0.43) | DNM1THRBLPAR1LPAR3LPAR2 | |
| SCHEMBL27478603 | 0.91 | DNM1 (0.47) | DNM1THRBTSHRLPAR1LPAR3 | |
| SCHEMBL9602049 | 0.90 | LMNA (0.48) | DNM1LMNATHRBTSHRMEN1 | |
| SCHEMBL27479414 | 0.88 | DNM1 (0.43) | DNM1THRBLPAR1LPAR3LPAR2 | |
| SCHEMBL8114496 | 0.86 | ADRB2 (0.36) | DNM1TSHR | |
| SCHEMBL11445837 | 0.85 | MEN1 (0.45) | DNM1LMNATHRBTSHRLPAR1 | |
| SCHEMBL31296272 | 0.83 | ADRB2 (0.38) | DNM1LMNATSHR | |
| SCHEMBL9865981 | 0.82 | DNM1 (0.47) | DNM1THRBTSHRLPAR1LPAR3 | |
| SCHEMBL8108490 | 0.81 | ADRB2 (0.36) | DNM1TSHR | |
| SCHEMBL8108694 | 0.81 | DNM1 (0.35) | DNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319150-A | Chloroalkylation of aromatic compounds | ALBEMARLE CORPORATION (US) | 1994-06-07 | — | — | US | disclosed |
| US-5136115-A | BROMOALKYLATION OF AROMATIC COMPOUNDS | ALBERMARLE CORPORATION | 1992-08-04 | — | — | US | disclosed |
| EP-0369728-A1 | Haloalkylation of aromatic compounds | ETHYL CORPORATION (US) | 1990-05-23 | — | — | EP | disclosed |