Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933618 | 0.95 | EPHX1 (0.51) | EPHX1EPHX2LTA4HGPR84PPARA | |
| SCHEMBL934358 | 0.94 | FAAH (0.51) | EPHX1EPHX2LTA4HGPR84PPARA | |
| SCHEMBL5723863 | 0.92 | EPHX1 (0.50) | EPHX1EPHX2LTA4HGPR84FFAR1 | |
| SCHEMBL22721288 | 0.87 | FFAR1 (0.52) | EPHX1EPHX2LTA4HGPR84PPARA | |
| SCHEMBL24264814 | 0.87 | HDAC3 (0.55) | EPHX2LTA4HPPARAFFAR1FFAR4 | |
| SCHEMBL934552 | 0.81 | CHRM2 (0.51) | EPHX1PPARAFFAR1FFAR4DAO | |
| SCHEMBL328546 | 0.81 | MAPK8 (0.55) | EPHX1EPHX2LTA4HMAPK8 | |
| SCHEMBL28018674 | 0.81 | F2RL1 (0.51) | EPHX1EPHX2LTA4HGPR84PPARA | |
| SCHEMBL27680835 | 0.80 | EPHX1 (0.44) | EPHX1EPHX2LTA4HGPR84PPARA | |
| SCHEMBL10972858 | 0.80 | FAAH (0.54) | EPHX1EPHX2LTA4HGPR84PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1780821-A | Heterocyclic kinase inhibitors. | ABBOTT LAB (US) | 2006-05-31 | — | — | CN | claimed |
| WO-2011037833-A2 | NOVEL N-BENZYLAMIDE SUBSTITUTED DERIVATIVES OF 2-(ACYLAMIDO)ACETIC ACID AND 2-(ACYLAMIDO)PROPIONIC ACIDS: POTENT NEUROLOGICAL AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2011-03-31 | — | — | WO | disclosed |
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |
| CN-1780821-A | Heterocyclic kinase inhibitors. | ABBOTT LAB (US) | 2006-05-31 | — | — | CN | disclosed |