Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.51 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933618 | 0.98 | EPHX1 (0.51) | FAAHCES1EPHX1LTA4HEPHX2 | |
| SCHEMBL934008 | 0.94 | EPHX1 (0.49) | FAAHEPHX1LTA4HEPHX2GPR84 | |
| SCHEMBL5723863 | 0.89 | EPHX1 (0.50) | EPHX1LTA4HEPHX2GPR84FFAR1 | |
| SCHEMBL10972858 | 0.86 | FAAH (0.54) | FAAHCES1EPHX1LTA4HEPHX2 | |
| SCHEMBL11635705 | 0.86 | FAAH (0.54) | FAAHCES1EPHX1LTA4HEPHX2 | |
| SCHEMBL22721288 | 0.84 | FFAR1 (0.52) | EPHX1LTA4HEPHX2GPR84FFAR1 | |
| SCHEMBL3872336 | 0.84 | HDAC1 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL934428 | 0.82 | PPARG (0.52) | FAAHCES1EPHX1HDAC1HDAC6 | |
| SCHEMBL4046194 | 0.82 | FFAR1 (0.56) | FAAHCES1FFAR1FFAR4 | |
| SCHEMBL675019 | 0.81 | MAPT (0.57) | FAAHCES1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |