Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10371881 | 0.87 | ALDH1A1 (0.43) | ALDH1A1MEN1LMNAHPGDHTT | |
| SCHEMBL7363800 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MEN1LMNAHPGDHTT | |
| SCHEMBL7319755 | 0.84 | ALDH1A1 (0.41) | ALDH1A1MEN1LMNAHPGDHTT | |
| SCHEMBL14237178 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MEN1LMNAHPGDHTT | |
| SCHEMBL3583694 | 0.80 | PKM (0.49) | ALDH1A1MEN1LMNAHPGDHTT | |
| SCHEMBL1975251 | 0.78 | LMNA (0.45) | ALDH1A1MEN1LMNAHPGDKMT2A | |
| SCHEMBL7393410 | 0.78 | ALDH1A1 (0.37) | ALDH1A1MEN1LMNAHPGDHTT | |
| SCHEMBL27887946 | 0.76 | TPMT (0.47) | ALDH1A1MEN1LMNAHPGDHTT | |
| SCHEMBL6772316 | 0.75 | HSD17B10 (0.44) | ALDH1A1MEN1LMNAHPGDHTT | |
| SCHEMBL19888383 | 0.75 | SMN1; SMN2 (0.44) | ALDH1A1MEN1LMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600955-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-06-15 | — | — | EP | disclosed |
| WO-1993003725-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-03-04 | — | — | WO | disclosed |