SCHEMBL934055

SCHEMBL934055

Brc1cnc2cc(Br)cnc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 5/20 0.52
HTT P42858 3/20 0.48
KMT2A Q03164 1/20 0.48
ALDH1A1 P00352 4/20 0.39
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPK1 P28482 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
AURKA O14965 2/20 0.38
DAPK3 O43293 2/20 0.38
JAK2 O60674 2/20 0.38
MAP4K4 O95819 2/20 0.38
PAK4 O96013 2/20 0.38
ABL1 P00519 2/20 0.38
RET P07949 2/20 0.38
FGFR1 P11362 2/20 0.38
PDGFRA P16234 2/20 0.38
FLT1 P17948 2/20 0.38
LTK P29376 2/20 0.38
GRK5 P34947 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29470857 1.00 DYRK1A (0.52) DYRK1AHTTKMT2AALDH1A1MAPT
SCHEMBL12565427 0.84 HTT (0.44) DYRK1AHTTKMT2AALDH1A1MAPT
SCHEMBL30466588 0.83 DYRK1A (0.41) DYRK1AHTTKMT2AALDH1A1MAPT
SCHEMBL29796470 0.81 HTT (0.53) DYRK1AHTTKMT2AALDH1A1MAPT
SCHEMBL335171 0.81 HTT (0.53) DYRK1AHTTKMT2AALDH1A1MAPT
SCHEMBL29967332 0.79 DYRK1A (0.38) DYRK1AHTTKMT2AALDH1A1MAPT
SCHEMBL208674 0.79 DYRK1A (0.38) DYRK1AHTTKMT2AALDH1A1MAPT
SCHEMBL17548779 0.78 NPC1 (0.53) DYRK1AALDH1A1MAPTSMN1; SMN2MAPK1
SCHEMBL30874963 0.77 HTT (0.46) DYRK1AHTTKMT2AALDH1A1MAPT
SCHEMBL29171765 0.77 HTT (0.46) DYRK1AHTTKMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025123383-A1 ORGANIC COMPOUND AND DISPLAY PANEL 武汉华星光电半导体显示技术有限公司 2025-06-19 WO disclosed
US-20250197427-A1 ORGANIC COMPOUNDS AND DISPLAY PANELS WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2025-06-19 US disclosed
WO-2024258154-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 진웅산업 2024-12-19 WO disclosed
WO-2024258156-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 진웅산업 2024-12-19 WO disclosed
WO-2024258158-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME 주식회사 진웅산업 2024-12-19 WO disclosed
CN-117720565-A Organic compound and display panel 武汉华星光电半导体显示技术有限公司 2024-03-19 CN disclosed
CN-114213409-A Material for organic electroluminescent element, and consumer product 上海八亿时空先进材料有限公司 2022-03-22 CN disclosed
CN-106554352-B Polycyclic aromatic hydrocarbon derivative containing naphthyridine group and application thereof 北京鼎材科技有限公司 2020-12-08 CN disclosed
US-10629819-B2 Compound for organic electronic element, organic electrical element using compound, and electronic device comprising same DUK SAN NEOLUX CO., LTD (KR) 2020-04-21 US disclosed
US-10381574-B2 Compound for organic electronic element, organic electrical element using compound, and electronic device comprising same DUK SAN NEOLUX CO., LTD. (KR) 2019-08-13 US disclosed
US-20050272736-A1 Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands ABBVIE INC. 2005-12-08 US disclosed
US-20050272728-A1 Bicyclic-substituted amines having cyclic-substituted monocyclic substituents ABBVIE INC. 2005-12-08 US disclosed
WO-2005113536-A2 TRI- AND BI-CYCLIC HETEROARYL HISTAMINE-3 RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 2005-12-01 WO disclosed
WO-2005113551-A1 BICYCLIC-SUBSTITUTED AMINES HAVING CYCLIC-SUBSTITUTED MONOCYCLIC SUBSTITUENTS ABBOTT LABORATORIES (US) 2005-12-01 WO disclosed
US-20050256309-A1 Tri-and bi-cyclic heteroaryl histamine-3 receptor ligands ABBOTT LABORATORIES 2005-11-17 US disclosed
US-20050256118-A1 Bicyclic-substituted amines having cyclic-substituted monocyclic substituents ABBOTT LABORATORIES 2005-11-17 US disclosed
EP-1569637-A1 BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS Abbott Laboratories (US) 2005-09-07 EP disclosed
US-20040152704-A1 Bicyclic-substituted amines as histamine-3 receptor ligands ABBVIE INC. 2004-08-05 US disclosed
WO-2004043458-A1 BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS ABBOTT LABORATORIES (US) 2004-05-27 WO disclosed
US-20040092521-A1 Bicyclic-substituted amines as histamine-3 receptor ligands ABBOTT LABORATORIES 2004-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10629819-B2 Compound for organic electronic element, organic electrical element using compound, and electronic device comprising same ORAI2, VDAC2, PIEZO1 DYRK1A 4019/4885HTT 666/4885KMT2A 727/4885
US-20050272736-A1 Tri- and bi-cyclic heteroaryl histamine-3 receptor ligands HRH3, HRH4, HRH2 DYRK1A 436/4885HTT 1732/4885KMT2A 785/4885
US-20050272728-A1 Bicyclic-substituted amines having cyclic-substituted monocyclic substituents HRH3, HRH4, HRH2 DYRK1A 577/4885HTT 2795/4885KMT2A 523/4885
US-20050256118-A1 Bicyclic-substituted amines having cyclic-substituted monocyclic substituents HRH3, HRH4, HRH2 DYRK1A 577/4885HTT 2795/4885KMT2A 523/4885
US-10381574-B2 Compound for organic electronic element, organic electrical element using compound, and electronic device comprising same ORAI2, VDAC2, PIEZO1 DYRK1A 4019/4885HTT 666/4885KMT2A 727/4885
US-20050256309-A1 Tri-and bi-cyclic heteroaryl histamine-3 receptor ligands HRH3, HRH4, HRH2 DYRK1A 436/4885HTT 1732/4885KMT2A 785/4885
US-20250197427-A1 ORGANIC COMPOUNDS AND DISPLAY PANELS CHRM1, CHRM2, C1S DYRK1A 2720/4885HTT 4043/4885KMT2A 3867/4885
US-20040092521-A1 Bicyclic-substituted amines as histamine-3 receptor ligands HRH3, HRH4, HRH1 DYRK1A 4076/4885HTT 2298/4885KMT2A 1805/4885
US-20040152704-A1 Bicyclic-substituted amines as histamine-3 receptor ligands HRH3, HRH4, HRH1 DYRK1A 3693/4885HTT 2308/4885KMT2A 1877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.