Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.51 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9338923 | 0.85 | ABCG2 (0.44) | ABCG2CA12CA9FAAH | |
| SCHEMBL9338906 | 0.83 | ABCG2 (0.52) | ABCG2HSPB1CA12CA9MAOA | |
| SCHEMBL1314780 | 0.81 | ABCG2 (0.52) | ABCG2CA12CA9MAOAMAOB | |
| SCHEMBL11792502 | 0.79 | HSPB1 (0.54) | HSPB1ARCACNA1CTRPA1SCN4A | |
| SCHEMBL16440282 | 0.75 | CACNA1C (0.59) | HSPB1ARFAAHCACNA1CTRPA1 | |
| SCHEMBL1315553 | 0.75 | ABCG2 (0.52) | ABCG2MAOAMAOB | |
| SCHEMBL9339622 | 0.74 | HPGD (0.48) | CA12CA9MAOAMAOB | |
| SCHEMBL387869 | 0.72 | CYP1A2 (0.46) | ABCG2 | |
| SCHEMBL4368827 | 0.72 | AR (0.58) | HSPB1ARTRPA1SCN4A | |
| SCHEMBL159814 | 0.72 | LTA4H (0.61) | CA12CA9MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363308-B1 | Ethers | CIBA GEIGY AG (CH) | 1994-06-01 | — | — | EP | claimed |