Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340053 | 0.82 | PDK2 (0.41) | PDK2SLC11A2BACE1 | |
| SCHEMBL9340806 | 0.82 | TP53 (0.37) | TP53ALDH1A1PDK2ADRA1AMAPT | |
| SCHEMBL9339974 | 0.79 | ALDH1A1 (0.36) | TP53ALDH1A1CA1CA2CA4 | |
| SCHEMBL9339933 | 0.79 | TP53 (0.40) | TP53ALDH1A1PDK2CA1CA2 | |
| SCHEMBL8311974 | 0.74 | BACE1 (0.37) | TP53ALDH1A1MAPTSLC6A2KMT2A | |
| SCHEMBL8310390 | 0.71 | SLC6A2 (0.36) | TP53ALDH1A1SLC6A2NR3C1BACE1 | |
| SCHEMBL9340819 | 0.69 | APP (0.40) | TP53ALDH1A1PDK2TDP1L3MBTL1 | |
| SCHEMBL30725601 | 0.68 | TP53 (0.62) | TP53ALDH1A1ADRA1AMAPTL3MBTL1 | |
| SCHEMBL29143018 | 0.68 | TP53 (0.62) | TP53ALDH1A1ADRA1AMAPTL3MBTL1 | |
| SCHEMBL9344209 | 0.67 | TP53 (0.36) | TP53ALDH1A1PDK2ADRA1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356915-A | Antihypertensive and bronchodilator agents | J. URIACH & CIA. S.A. (ES) | 1994-10-18 | — | — | US | disclosed |
| EP-0600147-A1 | Tetralones with pharmacological activity, compositions containing them and process for their preparation | J. URIACH & CIA. S.A. (ES) | 1994-06-08 | — | — | EP | disclosed |