Sugi Predict

Sugi Predict / Compounds / SCHEMBL700677

SCHEMBL700677

SCHEMBL700677

CCN(CC)c1ccc2c(C)c(Br)c(=O)oc2c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 13/20 0.73
▸ KDM4E B2RXH2 10/20 0.73
▸ GLA P06280 7/20 0.73
▸ MAPT P10636 7/20 0.73
▸ MEN1 O00255 7/20 0.73
▸ KMT2A Q03164 7/20 0.73
▸ ATM Q13315 6/20 0.73
▸ HTT P42858 6/20 0.73
▸ L3MBTL1 Q9Y468 6/20 0.73
▸ CASP1 P29466 6/20 0.73
▸ CASP7 P55210 6/20 0.73
▸ HSD17B10 Q99714 6/20 0.73
▸ TDP1 Q9NUW8 4/20 0.73
▸ CYP3A4 P08684 3/20 0.73
▸ TP53 P04637 3/20 0.73
▸ NPSR1 Q6W5P4 3/20 0.73
▸ LMNA P02545 2/20 0.73
▸ CYP1A2 P05177 2/20 0.73
▸ CYP2C9 P11712 2/20 0.73
▸ CYP2C19 P33261 2/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21457006 0.89 ALDH1A1 (0.59) ALDH1A1KDM4EGLAMAPTMEN1
SCHEMBL11296750 0.88 ALDH1A1 (0.78) ALDH1A1KDM4EGLAMAPTMEN1
SCHEMBL21456974 0.87 ALDH1A1 (0.56) ALDH1A1KDM4EGLAMAPTMEN1
SCHEMBL12651890 0.84 ALDH1A1 (0.72) ALDH1A1KDM4EGLAMAPTMEN1
SCHEMBL21457065 0.84 CCR4 (0.56) ALDH1A1KDM4EGLAMAPTMEN1
SCHEMBL24589860 0.83 ALDH1A1 (1.00) ALDH1A1KDM4EGLAMAPTMEN1
SCHEMBL3838409 0.83 ALDH1A1 (0.51) ALDH1A1KDM4EGLAMAPTMEN1
SCHEMBL24861952 0.83 ALDH1A1 (0.71) ALDH1A1KDM4EGLAMAPTMEN1
SCHEMBL7730304 0.81 ALDH1A1 (0.68) ALDH1A1KDM4EGLAMAPTMEN1
SCHEMBL21456977 0.81 ALDH1A1 (0.67) ALDH1A1KDM4EGLAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111606896-B Use of fluorescent probes for the preparation of reagents for the detection of nerve agents 湖南科技大学 2022-10-14 — — CN claimed
CN-111606896-A Fluorescent probe capable of visually detecting nerve toxicant for multiple times at comparable rate, preparation and application 湖南科技大学 2020-09-01 — — CN claimed
CN-110082321-B Fluorescent nano material for detecting various organic amines in water and application thereof 中山大学 2020-06-16 — — CN claimed
US-11945806-B2 Stabilization of amyloidogenic immunoglobulin light chains THE SCRIPPS RESEARCH INSTITUTE 2024-04-02 — — US disclosed
CN-114349729-B Coumarin derivative and preparation method and application thereof 包头稀土研究院 2023-07-18 — — CN disclosed
CN-115867544-A Substituted coumarin dyes and their use as fluorescent labels 伊鲁米纳剑桥有限公司 2023-03-28 — — CN disclosed
EP-3553054-B1 FLUORESCENT COUMARIN COMPOUNDS AND METHOD OF SYNTHESIS THEREOF UNIV EVORA (PT) 2023-01-11 — — EP disclosed
EP-3553054-B1 FLUORESCENT COUMARIN COMPOUNDS AND METHOD OF SYNTHESIS THEREOF UNIV EVORA (PT) 2023-01-11 — — EP disclosed
CN-111606896-B Use of fluorescent probes for the preparation of reagents for the detection of nerve agents 湖南科技大学 2022-10-14 — — CN disclosed
US-20220204485-A1 STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS THE SCRIPPS RESEARCH INSTITUTE 2022-06-30 — — US disclosed
CN-114349729-A Coumarin derivative and preparation method and application thereof 包头稀土研究院 2022-04-15 — — CN disclosed
US-20100298573-A1 FLUORESCENT AGENT HAVING ETHYNYL GROUP NIPPON CHEMICAL WORKS CO., LTD (JP) 2010-11-25 — — US disclosed
EP-2063915-A1 FLUOROGENIC PROTEIN KINASE SUBSTRATES Invitrogen Corporation (US) 2009-06-03 — — EP disclosed
US-20080194522-A1 Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE 2008-08-14 — — US disclosed
US-20080194522-A1 Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE 2008-08-14 — — US disclosed
US-20080194522-A1 Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE 2008-08-14 — — US disclosed
WO-2008016762-A1 FLUOROGENIC PROTEIN KINASE SUBSTRATES INVITROGEN CORPORATION (US) 2008-02-07 — — WO disclosed
WO-2008016762-A1 FLUOROGENIC PROTEIN KINASE SUBSTRATES INVITROGEN CORPORATION (US) 2008-02-07 — — WO disclosed
US-20080009026-A1 FLUOROGENIC PROTEIN KINASE SUBSTRATES INVITROGEN CORPORATION (US) 2008-01-10 — — US disclosed
US-20080009026-A1 FLUOROGENIC PROTEIN KINASE SUBSTRATES INVITROGEN CORPORATION (US) 2008-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298573-A1 FLUORESCENT AGENT HAVING ETHYNYL GROUP IK, CCNE1, TAS2R45 ALDH1A1 105/4885KDM4E 3868/4885GLA 1271/4885
US-20080194522-A1 Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) MAOA, MAOB, COMT ALDH1A1 181/4885KDM4E 1183/4885GLA 185/4885
US-20220204485-A1 STABILIZATION OF AMYLOIDOGENIC IMMUNOGLOBULIN LIGHT CHAINS TTR, MAP1LC3B, SAAL1 ALDH1A1 2072/4885KDM4E 4575/4885GLA 449/4885
US-11945806-B2 Stabilization of amyloidogenic immunoglobulin light chains TTR, MAP1LC3B, SAAL1 ALDH1A1 2072/4885KDM4E 4575/4885GLA 449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.