Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 12/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 10/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 7/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21571314 | 0.76 | CYP2A6 (0.35) | — | |
| SCHEMBL5658589 | 0.73 | SYK (0.35) | POLBCYP1A2CYP3A4CLK4MAPK1 | |
| SCHEMBL4851533 | 0.72 | PI4KA (0.48) | CHEK1AURKACYP1A2CLK4ALDH1A1 | |
| SCHEMBL5551347 | 0.71 | MAP4K4 (0.40) | CYP1A2CYP3A4CLK4ALDH1A1MAPK1 | |
| SCHEMBL22116603 | 0.71 | SLC40A1 (0.37) | CHEK1CLK4ALDH1A1HSD17B10MEN1 | |
| SCHEMBL2184445 | 0.69 | EGFR (0.68) | POLBCYP1A2CYP3A4CLK4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27318612 | 0.68 | EGFR (0.66) | POLBCYP1A2CYP3A4CLK4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL14775621 | 0.68 | EGFR (0.66) | POLBCYP1A2CYP3A4CLK4ALDH1A1 | |
| SCHEMBL1951437 | 0.68 | CCR1 (0.43) | POLBCYP1A2ALDH1A1HSP90AA1 | |
| SCHEMBL27688047 | 0.67 | CCR1 (0.42) | POLBCYP1A2ALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5373011-A | Substituted quinazoline fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-12-13 | — | — | US | disclosed |
| US-5270466-A | Substituted quinazoline fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1993-12-14 | — | — | US | disclosed |