SCHEMBL9341835

SCHEMBL9341835

CC(=O)N(C)[Si](c1ccccc1)(c1ccccc1)N(C)C(C)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
MAPT P10636 2/20 0.39
OPRM1 P35372 1/20 0.39
OPRL1 P41146 1/20 0.39
TSPO P30536 1/20 0.37
ELANE P08246 1/20 0.37
ALDH1A1 P00352 2/20 0.36
TSHR P16473 2/20 0.36
GLA P06280 1/20 0.36
KMT2A Q03164 3/20 0.36
KDM4E B2RXH2 2/20 0.36
EGFR P00533 2/20 0.36
USP2 O75604 1/20 0.36
NAPRT Q6XQN6 1/20 0.35
HSD17B10 Q99714 1/20 0.35
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
HPGD P15428 1/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11544966 0.83 CES2 (0.41) CES2CES1MAPTOPRM1OPRL1
SCHEMBL8435728 0.83 CES2 (0.41) CES2CES1MAPTOPRM1OPRL1
SCHEMBL11516708 0.81 MAPT (0.42) CES2CES1MAPTOPRM1OPRL1
SCHEMBL9148153 0.81 MAPT (0.42) CES2CES1MAPTOPRM1OPRL1
SCHEMBL11405506 0.78 KMT2A (0.38) CES2CES1OPRM1OPRL1ALDH1A1
SCHEMBL435723 0.71 ESR1 (0.37) MAPTOPRM1OPRL1ALDH1A1TSHR
SCHEMBL14760071 0.67 CES2 (0.48) CES2CES1MAPTALDH1A1TSHR
SCHEMBL1130961 0.67 CES2 (0.48) CES2CES1MAPTALDH1A1TSHR
SCHEMBL16706156 0.67 ESR1 (0.44) CES2CES1MAPTALDH1A1TSHR
SCHEMBL14760301 0.67 CES2 (0.48) CES2CES1MAPTALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116477878-B Fertilizer slow-release organic silicon composite flowerpot and preparation method thereof 万华化学集团股份有限公司 2025-04-01 CN claimed
CN-116477878-A Fertilizer slow-release organic silicon composite flowerpot and preparation method thereof 万华化学集团股份有限公司 2023-07-25 CN claimed
CN-116477878-B Fertilizer slow-release organic silicon composite flowerpot and preparation method thereof 万华化学集团股份有限公司 2025-04-01 CN disclosed
CN-116477878-A Fertilizer slow-release organic silicon composite flowerpot and preparation method thereof 万华化学集团股份有限公司 2023-07-25 CN disclosed
US-5288832-A Poly(silethynylenedisiloxane) and method for the manufacture thereof DOW CORNING JAPAN, LTD. (JP) 1994-02-22 US disclosed
EP-0553839-A2 Poly(Silethynylenedisiloxane) and method for the manufacture thereof DOW CORNING JAPAN, LTD. (JP) 1993-08-04 EP disclosed
US-4302571-A TERMINATED AT BOTH ENDS WITH SILANOIC HYDROXY GROUPS AND AN ORGANOSILANE OR ORGANOPOLYSILOXANE WITH HYDROLYZABLE GROUPS TO SERVE AS CROSSLINKING AGENTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1981-11-24 US disclosed
US-4252977-A Novel acetamide compounds and process for producing them GENERAL ELECTRIC COMPANY (US) 1981-02-24 US disclosed