SCHEMBL9148153

SCHEMBL9148153

CC(=O)N(C)[Si](C)(c1ccccc1)N(C)C(C)=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
ELANE P08246 1/20 0.39
OPRM1 P35372 1/20 0.38
OPRL1 P41146 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
HPGD P15428 2/20 0.37
TSPO P30536 1/20 0.36
ALDH1A1 P00352 1/20 0.35
GLA P06280 1/20 0.35
TSHR P16473 1/20 0.35
KMT2A Q03164 2/20 0.35
NAPRT Q6XQN6 1/20 0.34
HSD17B10 Q99714 1/20 0.34
RAB9A P51151 3/20 0.34
NPC1 O15118 1/20 0.34
KDM4E B2RXH2 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11516708 0.83 MAPT (0.42) MAPTCES2CES1ELANEOPRM1
SCHEMBL9341835 0.81 CES2 (0.41) MAPTCES2CES1ELANEOPRM1
SCHEMBL8435728 0.81 CES2 (0.41) MAPTCES2CES1ELANEOPRM1
SCHEMBL11544966 0.81 CES2 (0.41) MAPTCES2CES1ELANEOPRM1
SCHEMBL11413222 0.79 LMNA (0.35) MAPTOPRM1OPRL1ESR1ESR2
SCHEMBL9151256 0.76 MAPT (0.40) MAPTCES2CES1ESR1ESR2
SCHEMBL9151416 0.75 MAPT (0.42) MAPTCES2CES1ESR1ESR2
SCHEMBL1203911 0.72 ESR1 (0.41) MAPTOPRM1OPRL1ESR1ESR2
SCHEMBL14760178 0.69 MAPT (0.47) MAPTCES2CES1ESR1ESR2
SCHEMBL10862341 0.69 MAPT (0.47) MAPTCES2CES1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116477878-B Fertilizer slow-release organic silicon composite flowerpot and preparation method thereof 万华化学集团股份有限公司 2025-04-01 CN claimed
CN-116477878-A Fertilizer slow-release organic silicon composite flowerpot and preparation method thereof 万华化学集团股份有限公司 2023-07-25 CN claimed
CN-116477878-B Fertilizer slow-release organic silicon composite flowerpot and preparation method thereof 万华化学集团股份有限公司 2025-04-01 CN disclosed
CN-116477878-A Fertilizer slow-release organic silicon composite flowerpot and preparation method thereof 万华化学集团股份有限公司 2023-07-25 CN disclosed
EP-0381321-B1 Method for forming a crosslinkable pressure-sensitive adhesive construction containing an aminoxysilicon compound and an amidosilicon compound DOW CORNING (US) 1995-01-04 EP disclosed
EP-0271296-B1 SYNTACTIC SEALANTS DOW CORNING CORPORATION (US) 1993-01-20 EP disclosed
US-5086103-A Pressure-sensitive composition containing an aminoxysilicon compound DOW CORNING CORPORATION (US) 1992-02-04 US disclosed
US-5051472-A An addition polymer or a polyurethane rubber with a aminooxysilicon compound and an amidosilicon or amidosilane DOW CORNING CORPORATION (US) 1991-09-24 US disclosed
EP-0381321-A2 Method for forming a crosslinkable pressure-sensitive adhesive construction containing an aminoxysilicon compound and an amidosilicon compound DOW CORNING CORPORATION (US) 1990-08-08 EP disclosed
EP-0271296-A2 Syntactic sealants DOW CORNING CORPORATION (US) 1988-06-15 EP disclosed
US-4477606-A Water resistant room temperature vulcanizable polyorganosiloxane compositions and method for preparing same TORAY SILICONE CO., LTD. (JP) 1984-10-16 US disclosed
EP-0106363-A2 Water resistant room temperature vulcanizable polyorganosiloxane compositions and method for preparing same Toray Silicone Co., Ltd. (JP) 1984-04-25 EP disclosed
US-4252977-A Novel acetamide compounds and process for producing them GENERAL ELECTRIC COMPANY (US) 1981-02-24 US disclosed