Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 1/20 | 0.53 |
| ▸ | ACACB | O00763 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.44 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.44 |
| ▸ | ITGAL | P20701 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113636 | 0.81 | ALDH1A1 (0.53) | FCER2ACACBHDAC3MAPTNPC1 | |
| SCHEMBL29873370 | 0.81 | ALDH1A1 (0.53) | FCER2ACACBHDAC3MAPTNPC1 | |
| SCHEMBL13209550 | 0.79 | HTR2A (0.62) | FCER2CYP1A2 | |
| SCHEMBL1285448 | 0.79 | HTR2A (0.62) | FCER2CYP1A2 | |
| SCHEMBL11990779 | 0.79 | ACACB (0.52) | FCER2ACACBHDAC3MAPTNPC1 | |
| SCHEMBL5783367 | 0.79 | PKM (0.55) | FCER2ACACBHDAC3MAPTNPC1 | |
| SCHEMBL31711179 | 0.79 | PKM (0.55) | FCER2ACACBHDAC3MAPTNPC1 | |
| SCHEMBL21690018 | 0.79 | PKM (0.55) | FCER2ACACBHDAC3MAPTNPC1 | |
| SCHEMBL2297609 | 0.79 | PKM (0.55) | FCER2ACACBHDAC3MAPTNPC1 | |
| SCHEMBL464446 | 0.78 | ACACB (0.51) | FCER2ACACBHDAC3MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454243-A2 | TETRAZOLE DERIVATIVES | Merck Serono SA (CH) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |