SCHEMBL2297609

SCHEMBL2297609

NC(Cc1ccc2ncccc2c1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.55
SLC7A5 Q01650 4/20 0.51
HSD17B10 Q99714 3/20 0.51
PTGS1 P23219 2/20 0.51
KDM4E B2RXH2 2/20 0.51
USP2 O75604 1/20 0.51
EGFR P00533 1/20 0.51
LCK P06239 1/20 0.51
FYN P06241 1/20 0.51
ADORA3 P0DMS8 1/20 0.51
ALOX15 P16050 1/20 0.51
HTR2A P28223 1/20 0.51
PTGS2 P35354 1/20 0.51
RECQL P46063 1/20 0.51
HIF1A Q16665 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
TPH1 P17752 1/20 0.50
ALPI P09923 1/20 0.50
XIAP P98170 1/20 0.50
HDAC3 O15379 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5783367 1.00 PKM (0.55) PKMSLC7A5HSD17B10PTGS1KDM4E
SCHEMBL31711179 1.00 PKM (0.55) PKMSLC7A5HSD17B10PTGS1KDM4E
SCHEMBL21690018 1.00 PKM (0.55) PKMSLC7A5HSD17B10PTGS1KDM4E
SCHEMBL27725799 0.89 NPC1 (0.54) PKMSLC7A5PTGS1TPH1ALPI
SCHEMBL25177903 0.86 GRIK1 (0.48) HSD17B10KDM4EALOX15HDAC3MAPT
SCHEMBL30510316 0.86 GRIK1 (0.48) HSD17B10KDM4EALOX15HDAC3MAPT
SCHEMBL25177904 0.86 GRIK1 (0.48) HSD17B10KDM4EALOX15HDAC3MAPT
Dl-Phenylalanine SCHEMBL27783303 0.84 SLC7A5 (0.65) PKMSLC7A5HSD17B10PTGS1TPH1
Dl-Phenylalanine SCHEMBL28232423 0.84 SLC7A5 (0.65) PKMSLC7A5HSD17B10PTGS1TPH1
SCHEMBL14962738 0.84 ALOX15 (0.52) ALOX15HDAC3MAPTMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4401555-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2024-07-24 EP claimed
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2023-08-17 US claimed
WO-2023042201-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2023-03-23 WO claimed
CN-105143245-B Anti-scaling material 耶路撒冷希伯来大学伊森姆研究发展有限公司 2021-02-05 CN claimed
EP-2951195-B1 ANTIFOULING MATERIALS YISSUM RES DEV CO OF HEBREW UNIV JERUSALEM LTD (IL) 2020-02-19 EP claimed
EP-3374520-A1 BIOSENSORS Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2018-09-19 EP claimed
WO-2017081684-A1 BIOSENSORS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2017-05-18 WO claimed
US-9631100-B2 Antifouling materials YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2017-04-25 US claimed
US-20150368480-A1 ANTIFOULING MATERIALS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2015-12-24 US claimed
EP-2951195-A1 ANTIFOULING MATERIALS Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. (IL) 2015-12-09 EP claimed
WO-2014118779-A1 ANTIFOULING MATERIALS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2014-08-07 WO claimed
WO-2025094171-A1 SUPERHYDROPHOBIC COATING YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2025-05-08 WO disclosed
US-20250127167-A1 ANTIMICROBIAL PEPTIDES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2025-04-24 US disclosed
WO-2024261749-A1 ANTIMICROBIAL PEPTIDE-METAL COMPLEXES YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2024-12-26 WO disclosed
US-20240298636-A1 ANTIMICROBIAL AGENTS AND FILMS MADE THEREFROM YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2024-09-12 US disclosed
US-6465433-B1 SUCH AS N-(2-PYRIDINE)CARBONYL-L-PHENYLALANINE-L-LEUCINE BORONIC ACID; PROTEASOME INHIBITORS; REDUCING RATE OF MUSCLE PROTEIN DEGRADATION MILLENNIUM PHARMACEUTICALS, INC. 2002-10-15 US disclosed
US-6083903-A REDUCE RATE OF DEGRADATION OF PROTEINS IN ANIMAL LEUKOSITE, INC. (US) 2000-07-04 US disclosed
US-6066730-A Boronic ester and acid compounds, synthesis and uses PROSCRIPT, INC. 2000-05-23 US disclosed
US-5780454-A Boronic ester and acid compounds PROSCRIPT, INC. (US) 1998-07-14 US disclosed
WO-1996013266-A1 BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES PROSCRIPT, INC. (US) 1996-05-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES DNPEP, BCAT1, ANPEP PKM 3544/4885SLC7A5 21/4885HSD17B10 3966/4885
US-20150368480-A1 ANTIFOULING MATERIALS PFAS, FLNB, FLNA PKM 3572/4885SLC7A5 2272/4885HSD17B10 1687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.