Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | IAPP | P10997 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TRPM2 | O94759 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.33 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497882 | 0.90 | THRA (0.44) | THRATHRBTRPM2PLA2G1B | |
| SCHEMBL9341512 | 0.85 | MAOA (0.46) | MAOAMAOBSMN1; SMN2LMNAALOX5 | |
| SCHEMBL9342772 | 0.85 | THRA (0.44) | MAOBSMN1; SMN2LMNATHRATHRB | |
| SCHEMBL9338139 | 0.82 | HDAC4 (0.47) | SMN1; SMN2PTGS2THRATHRB | |
| SCHEMBL9341461 | 0.81 | PLA2G1B (0.47) | THRATHRBTRPM2TRPA1PLA2G1B | |
| SCHEMBL9342014 | 0.80 | MAOB (0.51) | MAOAMAOBSMN1; SMN2LMNAALOX5 | |
| SCHEMBL9338240 | 0.80 | THRA (0.49) | THRATHRBTRPM2TRPA1PLA2G1B | |
| SCHEMBL9341575 | 0.79 | MAOB (0.46) | MAOAMAOBSMN1; SMN2LMNAALOX5 | |
| SCHEMBL9339818 | 0.79 | MAOA (0.38) | MAOAMAOBSMN1; SMN2LMNAALOX5 | |
| SCHEMBL9339736 | 0.79 | HDAC4 (0.44) | THRATHRBPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |