Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | PKLR | P30613 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29763096 | 0.91 | LMNA (0.76) | HSD11B1LMNAGAAALDH1A1MEN1 | |
| SCHEMBL11959848 | 0.91 | LMNA (0.76) | HSD11B1LMNAGAAALDH1A1MEN1 | |
| SCHEMBL9347018 | 0.89 | POLB (0.63) | HSD11B1LMNAGAAPOLBALDH1A1 | |
| SCHEMBL12089451 | 0.84 | GCK (0.73) | HSD11B1LMNAMEN1KMT2A | |
| SCHEMBL12088782 | 0.83 | GCK (0.72) | HSD11B1LMNAPOLBALDH1A1MEN1 | |
| SCHEMBL12550071 | 0.81 | HSD11B1 (0.83) | HSD11B1LMNAGAAALDH1A1USP2 | |
| SCHEMBL12089633 | 0.81 | HSD11B1 (0.82) | HSD11B1GAAALDH1A1MEN1KMT2A | |
| SCHEMBL9342875 | 0.81 | LMNA (0.57) | HSD11B1LMNAGAAPOLBALDH1A1 | |
| SCHEMBL13974816 | 0.79 | LSS (0.55) | — | |
| SCHEMBL12169362 | 0.79 | LMNA (0.73) | HSD11B1LMNAGAAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328643-B1 | (alpha)-HYDROPEROXYISOPROPYLPHENYL COMPOUNDS AND PROCESS FOR THEIR PREPARATION | TERUMO CORP (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-5043142-A | Measuring peroxide-active substances | TERUMO KABUSHIKI KAISHA (JP) | 1991-08-27 | — | — | US | disclosed |
| EP-0328643-A1 | (alpha)-HYDROPEROXYISOPROPYLPHENYL COMPOUNDS AND PROCESS FOR THEIR PREPARATION | TERUMO KABUSHIKI KAISHA (JP) | 1989-08-23 | — | — | EP | disclosed |