Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.57 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.57 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.57 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9343545 | 0.89 | HSD11B1 (0.62) | POLBLMNAGAAKMT2AMEN1 | |
| SCHEMBL12169381 | 0.87 | LMNA (0.71) | POLBLMNASMN1; SMN2GAAKMT2A | |
| SCHEMBL13271402 | 0.84 | POLB (0.63) | POLBLMNASMN1; SMN2L3MBTL1EPHX2 | |
| SCHEMBL11959848 | 0.84 | LMNA (0.76) | LMNASMN1; SMN2ABCC9ABCC8KCNJ11 | |
| SCHEMBL29763096 | 0.84 | LMNA (0.76) | LMNASMN1; SMN2ABCC9ABCC8KCNJ11 | |
| SCHEMBL9347081 | 0.84 | POLB (0.58) | POLBLMNASMN1; SMN2ABCC9ABCC8 | |
| SCHEMBL18501704 | 0.83 | POLB (0.68) | POLBLMNASMN1; SMN2GAAKMT2A | |
| SCHEMBL12793245 | 0.83 | POLB (0.88) | POLBLMNASMN1; SMN2L3MBTL1GAA | |
| SCHEMBL24295449 | 0.81 | EPHX2 (0.75) | POLBLMNASMN1; SMN2ABCC9ABCC8 | |
| SCHEMBL28072234 | 0.80 | POLB (0.76) | POLBLMNASMN1; SMN2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328643-B1 | (alpha)-HYDROPEROXYISOPROPYLPHENYL COMPOUNDS AND PROCESS FOR THEIR PREPARATION | TERUMO CORP (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-5043142-A | Measuring peroxide-active substances | TERUMO KABUSHIKI KAISHA (JP) | 1991-08-27 | — | — | US | disclosed |
| EP-0328643-A1 | (alpha)-HYDROPEROXYISOPROPYLPHENYL COMPOUNDS AND PROCESS FOR THEIR PREPARATION | TERUMO KABUSHIKI KAISHA (JP) | 1989-08-23 | — | — | EP | disclosed |