SCHEMBL9344015

SCHEMBL9344015

CC(OCC(=O)N[C@H](C(=O)O)[C@@H](NC(=O)COC(C)(C(F)(F)F)C(F)(F)F)C(=O)O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MBTPS1 Q14703 1/20 0.34
CETP P11597 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9348125 0.73 TSHR (0.35)
SCHEMBL20002894 0.71
SCHEMBL9343508 0.66 ALDH1A1 (0.35) ALDH1A1
SCHEMBL9344541 0.65 CETP (0.35) CETP
SCHEMBL23166662 0.63 GRN (0.42) ALDH1A1
SCHEMBL5711380 0.63 MBTPS1 (0.50) MBTPS1ALDH1A1
SCHEMBL16445120 0.62 MBTPS1 (0.43) MBTPS1ALDH1A1
SCHEMBL16445117 0.62 MBTPS1 (0.43) MBTPS1ALDH1A1
SCHEMBL24263339 0.62 CTSK (0.35) MBTPS1ALDH1A1
SCHEMBL24350248 0.62 CTSK (0.35) MBTPS1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5362477-A 19F magnetic resonance imaging agents which include a nitroxide moiety MALLINCKRODT MEDICAL, INC. (US) 1994-11-08 US disclosed