Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 5/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859489 | 0.82 | PDE4D (0.34) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL9345699 | 0.82 | NAAA (0.33) | PDE4DNAAAPDE4APDE4BPDE4C | |
| SCHEMBL10551706 | 0.81 | NAAA (0.36) | PDE4DNAAA | |
| SCHEMBL21250764 | 0.80 | NAAA (0.45) | NAAA | |
| SCHEMBL9691813 | 0.80 | PDE4D (0.37) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL9649930 | 0.79 | NAAA (0.41) | PDE4DNAAAPDE4APDE4BPDE4C | |
| SCHEMBL10684490 | 0.78 | OPRM1 (0.38) | — | |
| SCHEMBL9354090 | 0.77 | PSEN1 (0.32) | — | |
| SCHEMBL10600595 | 0.76 | PDE4A (0.36) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL9345532 | 0.75 | NAAA (0.37) | PDE4DNAAAPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5275756-A | Pyrimidine ether compounds for electrooptical elements | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0469893-A1 | Fluorinated pyrimidine-phenyl optically active compounds and liquid crystal compositions thereof | Takasago International Corporation (JP) | 1992-02-05 | — | — | EP | disclosed |